|
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Dione-thiophene conjugate inhibits proliferation and metastasis of nasopharyngeal carcinoma cells through calcium binding protein-P down-regulation.
|
30822709 |
2019 |
|
Malignant Neoplasms
|
0.050 |
GeneticVariation
|
group |
BEFREE |
S100 proteins, the largest sub-group within the EF-hand protein family, are closely associated with cardiovascular diseases, various types of cancer, inflammation and autoimmune pathologies and brain diseases.
|
30392897 |
2019 |
|
Pancreatic carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Evaluation of novel highly specific antibodies to cancer testis antigen Centrin-1 for radioimmunoimaging and radioimmunotherapy of pancreatic cancer.
|
31309741 |
2019 |
|
Malignant neoplasm of pancreas
|
0.040 |
Biomarker
|
disease |
BEFREE |
Evaluation of novel highly specific antibodies to cancer testis antigen Centrin-1 for radioimmunoimaging and radioimmunotherapy of pancreatic cancer.
|
31309741 |
2019 |
|
Primary malignant neoplasm
|
0.030 |
GeneticVariation
|
group |
BEFREE |
S100 proteins, the largest sub-group within the EF-hand protein family, are closely associated with cardiovascular diseases, various types of cancer, inflammation and autoimmune pathologies and brain diseases.
|
30392897 |
2019 |
|
Amyloidosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Calnuc is a Golgi resident, calcium-binding protein, identified as chaperone protein and is reported to protect the cells against the cytotoxicity caused by amyloidosis and ER stress.
|
30710272 |
2019 |
|
Brain Diseases
|
0.010 |
GeneticVariation
|
group |
BEFREE |
S100 proteins, the largest sub-group within the EF-hand protein family, are closely associated with cardiovascular diseases, various types of cancer, inflammation and autoimmune pathologies and brain diseases.
|
30392897 |
2019 |
|
Cardiovascular Diseases
|
0.010 |
GeneticVariation
|
group |
BEFREE |
S100 proteins, the largest sub-group within the EF-hand protein family, are closely associated with cardiovascular diseases, various types of cancer, inflammation and autoimmune pathologies and brain diseases.
|
30392897 |
2019 |
|
Obesity
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Obesity is associated with declines in the CETN1 and CSPP1 abundance and compromise of both sperm morphology in mice and relevant clinical samples.
|
31651332 |
2019 |
|
Malignant neoplasm of testis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Evaluation of novel highly specific antibodies to cancer testis antigen Centrin-1 for radioimmunoimaging and radioimmunotherapy of pancreatic cancer.
|
31309741 |
2019 |
|
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
|
0.010 |
Biomarker
|
disease |
BEFREE |
Mice bearing PDAC MiaPaCa2 xenografts were imaged with microSPECT/CT and treated with <sup>213</sup> Bi- and <sup>177</sup> Lu-labeled antibodies to CETN1.
|
31309741 |
2019 |
|
Alzheimer's Disease
|
0.030 |
Biomarker
|
disease |
BEFREE |
Two months of CSP consumption reversed spatial memory deficits and the loss of a calcium binding protein calbindin-D<sub>28k</sub> in the hippocampus of AD mouse model.
|
29535835 |
2018 |
|
Diabetes
|
0.020 |
Biomarker
|
disease |
BEFREE |
The calcium binding protein S100B has been implicated in diabetic neuronal and vascular complications but has not been examined in the development of diabetes.
|
29499206 |
2018 |
|
Diabetes Mellitus
|
0.020 |
Biomarker
|
group |
BEFREE |
The calcium binding protein S100B has been implicated in diabetic neuronal and vascular complications but has not been examined in the development of diabetes.
|
29499206 |
2018 |
|
Non-Small Cell Lung Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Clinical significance of calcium-binding protein S100A8 and S100A9 expression in non-small cell lung cancer.
|
29733516 |
2018 |
|
Multiple Sclerosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The glial protein S100B, which belongs to a calcium binding protein family, is up-regulated in neurological diseases, like multiple sclerosis or glaucoma.
|
30319357 |
2018 |
|
Septicemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Hub genes with high degrees, including interleukin 1 receptor‑associated kinase 3 (IRAK3), S100 calcium‑binding protein (S100)A8, angiotensin II receptor‑associated protein (AGTRAP) and S100A9, were demonstrated to be associated sepsis.
|
29257295 |
2018 |
|
Memory impairment
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Two months of CSP consumption reversed spatial memory deficits and the loss of a calcium binding protein calbindin-D<sub>28k</sub> in the hippocampus of AD mouse model.
|
29535835 |
2018 |
|
Sepsis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Hub genes with high degrees, including interleukin 1 receptor‑associated kinase 3 (IRAK3), S100 calcium‑binding protein (S100)A8, angiotensin II receptor‑associated protein (AGTRAP) and S100A9, were demonstrated to be associated sepsis.
|
29257295 |
2018 |
|
Acute Cerebrovascular Accidents
|
0.010 |
Biomarker
|
disease |
BEFREE |
Clinical, imagiology, laboratory (biomarkers: C-reactive protein, D-dimer, and fibrinogen, and S100 calcium binding protein β [S100β]), and functionality assessments were conducted four different times: within 24 hours, and at 48 hours, 3 weeks, and 12 weeks after acute stroke.
|
30213243 |
2018 |
|
Peripheral Arterial Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Platelet RNA sequence profiling mapped a robust up-regulation of myeloid-related protein (MRP)-14 mRNA, a potent calcium binding protein heterodimer, in PAD.
|
29301628 |
2018 |
|
Diabetes
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
Even though captopril effectively reversed the diabetes-induced changes in calcium-binding protein 28-k and vitamin D receptor expression in the kidney as well as the expression of RAS components and bradykinin receptor-2 in bone tissue, treatment with captopril increased the osteoclast-covered bone surface, reduced the osteoblast-covered bone surface, down-regulated the expression of type 1 collagen and transcription factor runt-related transcription factor 2 (markers for osteoblastic functions), and up-regulated the expression of carbonic anhydrase II (marker for bone resorption).
|
28130181 |
2017 |
|
Diabetes Mellitus
|
0.020 |
AlteredExpression
|
group |
BEFREE |
Even though captopril effectively reversed the diabetes-induced changes in calcium-binding protein 28-k and vitamin D receptor expression in the kidney as well as the expression of RAS components and bradykinin receptor-2 in bone tissue, treatment with captopril increased the osteoclast-covered bone surface, reduced the osteoblast-covered bone surface, down-regulated the expression of type 1 collagen and transcription factor runt-related transcription factor 2 (markers for osteoblastic functions), and up-regulated the expression of carbonic anhydrase II (marker for bone resorption).
|
28130181 |
2017 |
|
Skin lesion
|
0.020 |
Biomarker
|
group |
BEFREE |
Psoriasin (S100A7) is an 11-kDa small calcium binding protein initially isolated from psoriatic skin lesions.
|
28393239 |
2017 |
|
Premenstrual syndrome
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The hypothalamus and hippocampus of each group modelling PMS displayed the following features: decreased expression of Ulip2, tubulin beta chain 15, <i>α</i> actin, and interleukin 1 receptor accessory protein; increased expression of kappa-B motif-binding phosphoprotein; decreased expression of hydrolase at the end of ubiquitin carboxy, albumin, and aldolase protein; and increased expression of M2 pyruvate kinase, panthenol-cytochrome C reductase core protein I, and calcium-binding protein.
|
28255462 |
2017 |